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  Normal breast
  Non-neoplastic lesions
  Benign epithelial

  Tumors of the nipple

  Lobular neoplasia

  Intraductal prolifera-
   tive lesions

  Invasive epithelial


  Mesenchymal tumors

  Hematopoetic and
   metastatic tumors

  IH-stainings, TMAs,
   FISH and CISH

Invasive ductal carcinoma
IDC represents ~70% of all invasive carcinomas of the breast. Carcinoma
cells invade in the tumor stroma, form a variable pattern of glandular structures,
or grow as solid sheets or nests. Epithelial cells are morphologically atypical,
which form the basis of differentiating carcinoma from radial scar and sclerosing
adenosis.The tumor is classified as IDC when features of special histologic
subtypes are not present, or present in a minority of the tumor.
  Classical IDC

IDC Grade 1

IDC Grade 2

IDC Grade 3

  IDC with extensive intra-
   ductal component (EIC+)
  IDC with lymphatic and
   vascular invasion
  IDC with lobular cancerisation
  IDC with choriocarcinomatous
  IDC with osteoclastic giant
  IDC typical to BRCA1 germ-
   line mutation carrier patients
  IDC after therapy

IDC after radiation therapy

IDC after preopera-
tive chemotherapy
  Recurrent IDC
Subcutaneous metastasis
Intramuscular metastasis
  Metastatic IDC
Lymph node metastasis

Sentinel node biopsies

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